mTOR

1. Mammalian Target of Rapamycin: A Signaling Kinase for every Aspect of Cellular LifeThomas Weichhart2. Biochemical and Pharmacological Inhibition of mTOR by Rapamycin and an ATP-Competitive mTOR InhibitorKer Yu and Lourdes Toral-Barza3. Evaluation of the Nutrient-Sensing mTOR PathwaySungki Hong, Aristotle M. Mannan and Ken Inoki4. mTOR Activity Under HypoxiaDouangsone D. Vadysirisack and Leif W. Ellisen5. Isolation of the mTOR Complexes by Affinity Purification Tattym Shaikenov, Olga Bulgakava, Rakhment I. Bersimbaev and Dos D. Sarbassov6. An in vitro Assay for the Kinase Activity of mTOR Complex 2Jingxiang Huang7. Overexpression or Downregulation of mTOR in Mammalian Cells Mahmoud Khalil and Ivan Gout 8. Dectection of Cytoplasmic and Nuclear Functions of mTOR by Fractionation Margit Rosner and Markus Hengstschläger9. Evaluation of Rapamycin-Induced Cell DeathLorenzo Galluzzi, Eugenia Morselli, Oliver Kepp, Ilio Vitale, Aména Ben Younes, Maria Chiara Maiuri and Guido Kroemer10. Evaluation of mTOR-Regulated mRNA TranslationValentina Iadevaia, Xuemin Wang, Zhong Yao, Leonard J. Foster and Christopher G. Proud11. A Genome-wide RNAi Screen for Polypeptides that Alter rpS6 PhosphorylationAngela Papageorgiou and Joseph Avruch12. Immunohistochemical Analysis of mTOR Activity in TissuesJinhee Kim, Nancy Otto, Claudio J. Conti, Irma B. Gimenz-Conti and Cheryl L. Walker13. Assessing Cell Size and Cell Cycle Regulation in Cells with Altered TOR ActivityMegan Cully and Julian Downward14. Quantitative Visualization of Authophagy Induction by mTOR InhibitorsBeat Nyfeler, Philip Bergman, Christopher J. Wilson and Leon O. Murphy15. The in vivo Evaluation of Active-Site TOR Inhibitors (asTORi) in Models of BCR-ABL+LeukemiaMatthew R. Janes and David A. Fruman16. Inducible raptor and rictor Kncokout Mouse Embryonic FibroblastsNadine Cybulski, Vittoria Zinzalla, and Michael N. Hall17. Expanding Human T Regulatory Cells with the mTOR- Inbibitor RapamycinManuela Battaglia, Angela Stabilini and Eleonora Tresoldi18. Rapamycin Induced Enhancement of Vaccine Efficacy in Mice Chinnaswamy Jagannath and Pearl Bakhru19. Utilizing a Retroviral RNAi System to Investigate in vivo mTOR Functions in T CellsKoichi Araki and Bogumila T. Konieczny20. Exploring Functional in Vivo Consequences of the Selective Genetic Ablation of mTOR Signaling in T Helper Lymphocytes Greg M. Delgoffe and Jonathan D. Powell 21. Evaluating the Therapeutic Potential of mTOR Inhibitors Using Mouse Genetics Huawei Li, Jennifer L. Cotton, David A. Guertin22. Inhibition of PI13K-Akt-mTOR Signaling in Glioblastoma by mTORC1/2 Inhibitors Qi-Wen Fan and Williams A. Weiss23. Assessing the Functions of mTOR in Human Embryonic Stem CellsJiaxi Zhou, Dong Li, and Fei Wang24. Video-EEG Monitoring Methods for Characterizing Rodent Models of Tuberous Sclerosis and Epilepsy Nicholas R. Rensing, Dongjun Guo, and Michael Wong25. A Genetic Model to Dissect the Role of Tsc-mTORC1 in Neuronal Cultures Duyu Nie and Mustufa Sahin 26. Tissue-Specific Ablation of Tsc1 in Pancreatic Beta-CellsHiroyuki Mori and Kun-Liang Guan27. A Mouse Model of Diet- Induced Obesity and Insulin REsistance Chao-Yung Want and James K. Liao28. Rapamycin as Immunosuppressant in Murine Transplantation Model Louis-Marie Charbonnier and Alain Le Moine29. Development of ATP-Competitive mTOR InhibitorsQingsong Liu, Seong A. Kang, Carson C. Thoreen, Wooyoung Hur, Jinhua Wang, Jae Won Chang, Andrew Markhard, Jianming Zhang, Taebo Sim, David M. Sabatini and Nathanael S. Gray... Mehr